SNPeBoT2 - Bioinformatics Job Portal

Submit New Job

Job Name

Transcription Factor Code/Name

Prediction Model

Use a fine-tuned model only if the submitted transcription factor belongs to that family. Otherwise use the general model.

Model Selection Guidance
The general SNPeBoT2 model is suitable for all transcription factors and is recommended by default. Fine-tuned models may improve prediction accuracy for TFs belonging specifically to the Homeodomain, bZIP, Ets, or bHLH families.

Use PDB specific potential?

Yes

PDB ID

Need a TF–DNA structure?
SNPeBoT2 requires a PDB structure of the transcription factor bound to DNA. If you do not already have one, you can generate a suitable model using ModCRE.

Follow ModCRE Tutorial 6 (Part 3) to build a TF–DNA complex and download the resulting PDB file for use with SNPeBoT2.

Open ModCRE

PDB File

Upload standard .pdb files only.

Choose ONE input method:

Upload a SNP input file OR
Enter one or more rsIDs

Do not provide both at the same time.

Option 1: Upload SNP Input File

SNP input file must contain tab-separated entries.

Option 2: Enter rsIDs

One rsID per line. Leave blank when uploading a SNP input file.

Submit Prior Predictions

Already have prediction results from a previous run? Upload one or more prediction result files here and SNPeBoT2 will combine them into a single job so you can go straight to running associations and enrichment — no PDB structure or new prediction run required.

Job Name

Transcription Factor Code/Name (optional)

Usually not needed — the TF is read directly from each variant ID in your prediction file(s). Only fill this in if your variant IDs don't already include a TF code.

Prediction Result File(s)

Select one or more prediction result files (same format as a SNPeBoT2 Predictions output file). They will be concatenated into a single job.

Submitted Jobs

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